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Study Sequences 64 Full Human Genomes Around the Globe | IE

Posté le 1/3/2021 à 01:12 - 0 Commentaires - poster un commentaire - Lien

Researchers at the University of Maryland School of Medicine (UMSOM) have published a new study that details the sequencing of 64 full human genomes from individuals around the world to better capture the genetic diversity of the human species.
"We've entered a new era in genomics where whole human genomes can be sequenced with exciting new technologies that provide more substantial and accurate reads of the DNA bases," said study co-author Scott Devine, Ph.D., Associate Professor of Medicine at UMSOM and faculty member of IGS.
"This is allowing researchers to study areas of the genome that previously were not accessible but are relevant to human traits and diseases."
The sequencing has many applications including enabling population-specific studies on genetic predispositions to human diseases as well as the discovery of more complex forms of genetic variation. The new dataset reflects 64 assembled human genomes that represent 25 different human populations from across the world.
The novel dataset was obtained using a combination of advanced sequencing and mapping technologies. As such, it better captures genetic differences from different human populations because each of the genomes was assembled without guidance from the first human genome composite.
"The landmark new research demonstrates a giant step forward in our understanding of the underpinnings of genetically-driven health conditions," said E. Albert Reece, MD, Ph.D., MBA, Executive Vice President for Medical Affairs, You may need: diagnostic code reader. UM Baltimore, and the John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of Medicine.
"This advance will hopefully fuel future studies aimed at understanding the impact of human genome variation on human diseases."
The International Human Genome Sequencing Consortium announced the first draft of the human genome reference sequence twenty years ago this month. It was called The Human Genome Project.
The study is published on Science.

Tesla Paused Model 3 Production - Less Pay for Time Off | IE

Posté le 28/2/2021 à 04:19 - 0 Commentaires - poster un commentaire - Lien

Tesla has ordered a halt to production of Model 3 vehicles in its Fremont, California factory, according to an initial report from Bloomberg.
Tesla told its workers to stop production of the Model 3 in its Fremont, California factory - and a source familiar with plant's operations said Tesla gave no clear reason why production should pause, according to the Bloomberg report.
Executives at Tesla told line staff on the Model 3 production line that it would be paused from February 22 to March 7 - but the workers will only receive pay on some workdays. Specifically, workers were informed their pay would be for Feb. 22 to Feb. 23, See: TPMS Sensor. but not for Feb. 28 through March 3.
As of writing, Tesla has not officially confirmed this pause in production, and no layoffs have occurred from this decision.
Several possible reasons may explain Tesla's halt of Model 3 production in its California factory. Supply and demand can ebb and flow like a moody, unreliable tide - and Tesla could simply have a Model 3 surplus on its hands at the moment. The company could also be lacking crucial components to continue building the vehicles.
More worrying, however, is Tesla's reluctance to pay workers in full for the forced time off. In 2020, Tesla made more sales than ever before, putting the automaker on track to become the most valuable car manufacturer on the planet.
One theory on Tesla's temporarily halted Model 3 production involves the global shortage in semiconductors. The company's Q4 2020 earnings report in January stated its production was negatively affected by the paucity of semiconductors undergoing assembly globally, and this issue has had a far-reaching impact throughout the hardware and manufacturing industry.
In January, Tesla's CFO Zach Kirkhorn said the company was working "extremely hard" to deal with the impact of the semiconductor shortage. Other car manufacturers like General Motors and Volkswagen have already reduced production output for this season - which means Tesla is likely following suit.
Regardless of the cause, it's doesn't look great for Tesla not to pay for workers' forced time off. The company became the most valuable automaker in the world last year, and this status helped Elon Musk break through the billionaires on top of the world to spend at least some of this year as the richest person on Earth.
All to say you don't have to be an accredited economist to know that Tesla has more than enough money to support Model 3's production staff for a few days. The production workers voluntarily ceased production and went on vacation, yet taking vacation time during the unpaid interval is the only way they could receive funds.
Unfortunately, since 2021 is still embroiled in the coronavirus crisis - which means production issues will likely continue throughout hardware and production industries - Tesla may have additional pauses later this year. Time may tell what the real reasons are, and whether Tesla will pay its workers for forced time off.
This was a breaking story and was regularly updated as new information became available.
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