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Costom Peptide Deltorphins, Dermorphins and Analogs 26/9/2019

Costom Peptide Deltorphins, Dermorphins and Analogs

DERMORPHIN ACETATE powder,DERMORPHIN powder, YmFHLMD-amide, a peptide first isolated from skin extracts of the South American frog Phyllomedusa sauvagei, corresponds to the predicted prodermorphin heptapepeptide. Deltorphin acts as a highly potent and fully selective agonist for the δ-opioid receptor.

Literature Reference : M.Amiche et al., Mol. Pharmacol., 35, 774 (1989) G.Kreil et al., Eur. J. Pharmacol., 162, 123 (1989) L.H.Lazarus et al., J. Biol. Chem., 264, 3047 (1989) A.Mor et al., FEBS Lett., 255, 269 (1989) S.Sagan et al., J. Biol. Chem., 264, 17100 (1989) P.Melchiorri et al., Eur. J. Pharmacol., 195, 201 (1991) S.Salvadori et al., J. Med. Chem., 34, 1656 (1991) L.H.Lazarus et al., J. Med. Chem., 34, 1350 (1991)
Application
1. Protects epithelial cell membranes in the stomach and restores them to their normal metabolism;
2. Acts as an antioxidant and protects the stomach from alcohol and smoking-induced damage;
3. Has anti-inflammatory properties and moderates production of interleukin-8;
4. Adheres to ulcerations, acts as a barrier between them and stomach acids and helps to heal them;
5. Inhibits activity of Helicobacter pylori bacteria;
6. Does not interfere with the production of prostaglandins essential to the mucosal lining of the stomach;
7.Strengthens these mucosal linings and stimulates production of protective mucous.

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